The Leibniz Institute for Neurobiology (LIN) in Magdeburg is an internationally renowned centre for learning and memory research. The Combinatorial NeuroImaging (CNI) Core Facility at LIN combines an outstanding range of imaging techniques for non-invasive human imaging, translational animal imaging and high resolution light microscopy. As a modern research infrastructure and dialogue platform we aim at supporting our local and external users in their scientific plans and projects with high efficiency and expertise. The scientific focus is directed at the combination of the different techniques from molecular to the systems level to gain a comprehensive knowledge of learning and memory processes. We refer to this integrative approach as "Combinatorial NeuroImaging".